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FRANK FREMONT-SMITH, M.D.

Arch Neurol Psychiatry. 1927;17(3):317-331.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The cerebrospinal fluid, noted by Galen, Vesalius and Valsalva, received its first important description from François Magendie, ¹ in 1825. His monograph, ² published in 1842, marked the beginning of numerous investigations stimulated by the increasing diagnostic and therapeutic importance of this fluid and its intimate relation to the problem of intracranial pressure.

Faivre, ³ in 1854, suggested that the choroid plexus was the source of the fluid, a view that has been accepted by most of the important investigators in this field; but it was not until 1919 that conclusive evidence was available. In that year, Dandy ⁴ demonstrated that obstruction of the foramen of Monro resulted in dilatation of the obstructed ventricle, but that such hydrocephalus never occurred if the choroid plexus of the same ventricle was removed.

Hassin, ⁵ however, seriously opposes the view that the choroid plexus is a source of cerebrospinal fluid. He believes that . . . [Full Text PDF of this Article]

Author Affiliations
BOSTON

From the Neurological Laboratory of the Massachusetts General Hospital and the Department of Neuropathology, Medical School of Harvard University.

Footnotes
Read at a Meeting of the Boston Society of Psychiatry and Neurology, Feb. 18, 1926.