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ROLE OF VITAMIN C IN METABOLISM OF NERVE TISSUE
HERMAN WORTIS, M.D.;
S. BERNARD WORTIS, M.D.;
FRANCES I. MARSH, A.B.
Arch Neurol Psychiatry 1938;39(5):1055-1066.
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The problem of nervous and mental diseases related to deficiences of specific food factors has recently been reviewed by one of us.1 It is now well established that vitamins A and B play an important role in the functioning of nerve tissue. Concerning the role of vitamin C in nervous economy little is known. It is our purpose in this paper to present, in addition to the results of our own studies, the recent data in this field, in an endeavor to understand the role of vitamin C in the metabolism of nerve tissue.
CHEMICAL STUDIES
Vitamin C is present in both the blood2 and the cerebrospinal fluid3 and is capable of passing from one to the other.4 It is present in the brain and spinal fluid only in its reduced form,3 whereas in the blood a portion of it occurs in the reversibly oxidizable
. . . [Full Text PDF of this Article]
Author Affiliations
NEW YORK
From the Department of Pathology, Laboratory of Experimental Neurology; the Psychiatric Division, and the Neurological Division of the Bellevue Hospital.
Footnotes
Read at the Sixty-Third Annual Meeting of the American Neurological Association, Atlantic City, N. J., June 4, 1937.
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