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OBSERVATIONS ON EFFECTS OF PHYSIOLOGIC VARIATIONS IN DEXTROSE, OXYGEN, POSTURE AND ACID-BASE BALANCE ON THE NORMAL ELECTROENCEPHALOGRAM

GEORGE L. ENGEL, M.D.; JOHN ROMANO, M.D.; EUGENE B. FERRIS, Jr., M.D.; JOSEPH P. WEBB, M.D.; CHARLES D. STEVENS, Ph.D.

Arch Neurol Psychiatry. 1944;51(2):134-146.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Although the gross configuration of the normal electroencephalogram remains remarkably constant in the same person from day to day, and even from year to year, there is nevertheless a significant physiologic zone of variation in frequency, voltage and regularity, which often cannot be appreciated by inspection alone. The fundamental elements controlling brain potentials have been defined by Dubner and Gerard¹; they include the intrinsic metabolic activity of the individual cells, the cellular membrane charges and the composition of the surrounding fluid mediums. As recorded by the electroencephalograph, the brain waves represent the electrical activity of masses of cortical cells discharging in a synchronous fashion. The nature of this synchronizing factor has not yet been clarified, but it may involve a group of cells acting as pacemakers. Alterations in the determinants of cellular metabolism, in membrane charge or in the composition of the surrounding fluid mediums generally affect frequency and . . . [Full Text PDF of this Article]

Author Affiliations
CINCINNATI

From the Departments of Psychiatry and Medicine, of the University of Cincinnati College of Medicine and the Cincinnati General Hospital.