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An Electromyographic Comparison with Dystrophia Myotonica in Man

A. R. McINTYRE, M.D.; A. L. BENNETT, M.D.; J. S. BRODKEY, A.B.

A.M.A. Arch Neurol Psychiatry. 1959;81(6):678-683.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The presence of fibrillation in the muscles of the Bar Harbor strain of dystrophic mice has previously been reported from this laboratory.¹ We have observed that the electromyogram from dystrophic mice of this strain is strikingly similar to that recorded from muscles of patients suffering from dystrophia myotonica. The muscles of such patients and animals are hyperirritable, and the records obtained by the insertion of a concentric needle electrode reveal the presence of short motor volleys of high frequency against a background of electrical activity characteristic of denervated muscle. In order to demonstrate the presence of fibrillation, free of the superimposed activity from innervated structures, it was decided to study the electrical activity of muscles in dystrophic mice and patients in whom the motor nerves were blocked.

The identification of characteristics common to both the dystrophy in this strain of mice and a particular form of dystrophy in man . . . [Full Text PDF of this Article]

Author Affiliations
Omaha

Footnotes
Accepted for publication Aug. 11, 1958.

Department of Physiology and Pharmacology, University of Nebraska College of Medicine.

This work was aided in part by a grant from the Muscular Dystrophy Association of America.